Ankylosing spondylitis (AS, or radiographic axial spondyloarthritis) is a form of arthritis that mainly affects the spine, even though other joints may turn out to be affected, as well. It causes inflammation of the spinal joints, which may lead to severe, chronic pain and discomfort.
The onset of AS is usually diagnosed in patients between 17 and 45 years of age (most commonly before 30). Males are diagnosed up to 3 times more often than females, and usually suffer more severe symptoms than women.
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